Catalytically inactive, purified RNase H1: A specific and sensitive probe for RNA–DNA hybrid imaging
Open Access
- 7 July 2021
- journal article
- research article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 220 (9)
- https://doi.org/10.1083/jcb.202101092
Abstract
Crossley et al. demonstrate that GFP-tagged, catalytically inactive RNase H1 protein is a versatile tool for imaging cellular R-loops. They also show that it isKeywords
Funding Information
- Leukemia and Lymphoma Society (5455-17)
- Jane Coffin Childs Memorial Fund for Medical Research (61-1755)
- National Institutes of Health (R01 GM119334, GM126600, R01 GM120607, P01 CA092584)
- V Foundation for Cancer Research (D2018.017)
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