: From December 2019 till now, the coronavirus disease pandemic has exposed the whole world to a new challenge where the survival of human beings faces an alarming phase. The human with its utmost intelligence is trying to find out the key to unlock the lock made by SARS-CoV-2, the causative virus of COVID-19. We, here briefly summarize the possible remedies so far introduced worldwide to combat the deadly pathogenic virus. The article includes the information of varieties of drugs applied globally: allopathic, homeopathic, Ayurveda, nanoparticle implicated protections and vaccinations trials along with other biotechnical applications in different countries. Our review work may be useful to scientists involved in researches in this field to know the global remedial aspects so far developed and also to create awareness among people to the present pandemic preventive mechanisms.