Neutrophil-Derived Oncostatin M Triggers Diverse Signaling Pathways during Pneumonia

Abstract
Pneumonia is a major public health concern, causing significant morbidity and mortality annually despite the broad use of antimicrobial agents. Underlying many of the severe sequelae of acute lung infections is dysfunction of the immune response, which remains incompletely understood yet is an attractive target of adjunct therapy in pneumonia.
Funding Information
  • HHS | NIH | National Institute of General Medical Sciences (GM120060)
  • HHS | NIH | National Center for Advancing Translational Sciences (TR001411)
  • HHS | NIH | National Center for Advancing Translational Sciences (TR001012)
  • HHS | NIH | National Heart, Lung, and Blood Institute (HL007035, HL120551, HL130582)
  • HHS | NIH | National Heart, Lung, and Blood Institute (HL111449)
  • HHS | NIH | National Heart, Lung, and Blood Institute (HL135756)