Paediatric High-Grade Intracranial Mesenchymal Chondrosarcoma: A Case Report with 6 Years of Follow-Up without Recurrence
- 5 November 2020
- journal article
- research article
- Published by S. Karger AG in Pediatric Neurosurgery
- Vol. 55 (5), 299-303
- https://doi.org/10.1159/000511021
Abstract
Introduction: Intracranial mesenchymal chondrosarcoma (MSC) is an extremely rare tumour that constitutes only 0.015% of all central nervous system tumours. These tumours usually originate from skull base synchondrosis and are often observed in young adults during their second and third decades of life. Despite the absence of a consensus regarding adjuvant radiotherapy, radical excision remains crucial for the prognosis of MSC. Case Presentation: We herein present the case of a young male patient with intracranial MSC, a malignant tumour, for which no consensus regarding its treatment has yet been established. The patient underwent radical excision followed by adjuvant radiotherapy. Histological analysis revealed a poorly differentiated tumour containing necrotic areas. Notably, no signs of recurrence had been observed after 6 years. Conclusion: The absence of recurrence over a long follow-up duration suggests the importance of radical excision and adjuvant radiotherapy.Keywords
This publication has 7 references indexed in Scilit:
- Is the IDH Mutation a Good Target for Chondrosarcoma Treatment?Current Molecular Biology Reports, 2020
- Mesenchymal chondrosarcoma: Prognostic factors and outcome in 113 patients. A European Musculoskeletal Oncology Society studyEuropean Journal Of Cancer, 2014
- Intracranial mesenchymal chondrosarcoma: case report and literature reviewBritish Journal Of Neurosurgery, 2012
- A systematic review of intracranial chondrosarcoma and survivalJournal of Clinical Neuroscience, 2009
- Management of Cranial Base ChondrosarcomasNeurosurgery, 2006
- Parafalcine chondrosarcoma: an unusual localization for a classical variant: Case report and review of the literatureSurgical Neurology, 2001
- Intracranial Extraskeletal Mesenchymal Chondrosarcoma: Case ReportNeurosurgery, 2000