Lung abscess secondary to lung cancer with a coinfection of Granulicatellaadiacens and other bacteria: a case report
Open Access
- 8 July 2021
- journal article
- research article
- Published by Springer Science and Business Media LLC in BMC Infectious Diseases
- Vol. 21 (1), 1-6
- https://doi.org/10.1186/s12879-021-06191-8
Abstract
Granulicatella adiacens is facultative anaerobic Gram-positive bacteria, which mainly involve bacterial endocarditis and bacteremia, but there are few reports of local suppurative infection. A case of lung abscess with a coinfection of Granulicatella adiacens and other bacteria in a lung cancer patient will be reported in this paper. To our knowledge, this is the first case report describing lung abscess due to G.adiacens. A 52-year-old Chinese woman was admitted to the hospital, She complained of coughing and expectoration for 1 month, shortness of breath for half a month, and dyspnea for 1 day. After a series of examinations, she was diagnosed with lung abscess, pleural effusion, and bronchogenic carcinoma. Draining pus culture demonstrated Granulicatella adiacens. After more than 5 weeks of antibiotic therapies in total, she gradually recovered to fight against lung cancer. This is the first reported lung abscess caused by G.adiacens. In immunosuppressed hosts, G.adiacens is a virulent pathogen associated with a spectrum of intrathoracic suppurative. Earlier diagnosis and proper drainage surgery with effective antibiotics treatment are very important, and antimicrobial treatment should be more than 5 weeks. When complex pulmonary infection interferes with the CT diagnosis, clinical suspicion of lung cancer should be increased if G.adiacens or Eikenella corrodens is detected from a pulmonary infection.Keywords
This publication has 30 references indexed in Scilit:
- Microbial transformation from normal oral microbiota to acute endodontic infectionsBMC Genomics, 2012
- Granulicatella infection: diagnosis and managementJournal of Medical Microbiology, 2012
- Guidelines for the diagnosis and antibiotic treatment of endocarditis in adults: a report of the Working Party of the British Society for Antimicrobial ChemotherapyJournal of Antimicrobial Chemotherapy, 2011
- An Unusual Causative Agent for an Orbital Abscess:Granulicatella AdiacensOrbit, 2011
- Ongoing Revolution in Bacteriology: Routine Identification of Bacteria by Matrix‐Assisted Laser Desorption Ionization Time‐of‐Flight Mass SpectrometryClinical Infectious Diseases, 2009
- Granulicatella adiacens and Abiotrophia defectiva bacteraemia characterized by 16S rRNA gene sequencingJournal of Medical Microbiology, 2003
- GranulicatellaandAbiotrophiaSpecies from Human Clinical SpecimensJournal of Clinical Microbiology, 2001
- Endocarditis Due to Rare and Fastidious BacteriaClinical Microbiology Reviews, 2001
- The Etiology and Antimicrobial Susceptibility Patterns of Microorganisms in Acute Community-Acquired Lung AbscessChest, 1995
- Lung abscess: A changing pattern of the diseaseThe American Journal of Surgery, 1985