Commemorating insulin's centennial: engineering insulin pharmacology towards physiology
Open Access
- 18 June 2021
- journal article
- review article
- Published by Elsevier in Trends in Pharmacological Sciences
- Vol. 42 (8), 620-639
- https://doi.org/10.1016/j.tips.2021.05.005
Abstract
No abstract availableKeywords
This publication has 120 references indexed in Scilit:
- Glucose-Reducing Effect of the ORMD-0801 Oral Insulin Preparation in Patients with Uncontrolled Type 1 Diabetes: A Pilot StudyPLOS ONE, 2013
- Tissue–Specific Insulin Signaling, Metabolic Syndrome, and Cardiovascular DiseaseArteriosclerosis, Thrombosis, and Vascular Biology, 2012
- A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic ControlDiabetes, 2012
- Design of the Novel Protraction Mechanism of Insulin Degludec, an Ultra-long-Acting Basal InsulinPharmaceutical Research, 2012
- In Vitro Metabolic and Mitogenic Signaling of Insulin Glargine and Its MetabolitesPLOS ONE, 2010
- Activation of the Insulin Receptor by Insulin and a Synthetic Peptide Leads to Divergent Metabolic and Mitogenic Signaling and ResponsesJournal of Biological Chemistry, 2007
- Reversible Insulin Self-Assembly under Carbohydrate ControlJournal of the American Chemical Society, 2005
- Preparation of an Insulin with Improved Pharmacokinetics Relative to Human Insulin through Consideration of Structural Homology with Insulin-Like Growth Factor IHormone Research, 1994
- Modeling absorption kinetics of subcutaneous injected soluble insulinJournal of Pharmacokinetics and Biopharmaceutics, 1989
- IMMUNOASSAY OF ENDOGENOUS PLASMA INSULIN IN MANJournal of Clinical Investigation, 1960