Inflammatory and mitogenic signals drive interleukin 23 subunit alpha (IL23A) secretion independent of IL12B in intestinal epithelial cells
Open Access
- 1 May 2020
- journal article
- research article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 295 (19), 6387-6400
- https://doi.org/10.1074/jbc.ra120.012943
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Education - Singapore (MOE2014-T2–2-143)
- MEXT | Japan Society for the Promotion of Science (JP18K07228)
This publication has 58 references indexed in Scilit:
- Expanding Diversity in Molecular Structures and Functions of the IL-6/IL-12 Heterodimeric Cytokine FamilyFrontiers in Immunology, 2016
- Insights into IL-23 biology: From structure to functionCytokine & Growth Factor Reviews, 2015
- IL-12-and IL-23 in health and diseaseCytokine & Growth Factor Reviews, 2014
- Interleukin-23 and T helper 17-type responses in intestinal inflammation: from cytokines to T-cell plasticityImmunology, 2011
- Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel diseaseNature Genetics, 2010
- The link between IL-23 and Th17 cell-mediated immune pathologiesSeminars in Immunology, 2007
- Transcriptional regulation of Th17 cell differentiationSeminars in Immunology, 2007
- Th17 cells: Effector T cells with inflammatory propertiesSeminars in Immunology, 2007
- IL23R Variation Determines Susceptibility But Not Disease Phenotype in Inflammatory Bowel DiseaseGastroenterology, 2007
- A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease GeneScience, 2006