Blocking the JAK2/STAT3 and ERK pathways suppresses the proliferation of gastrointestinal cancers by inducing apoptosis

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Abstract
Dysregulated crosstalk between different signaling pathways contributes to tumor development, including resistance to cancer therapy. In the present study,
Funding Information
  • National Natural Science Foundation of China (81770535, 81600595, 81503297, 81603340, 81773945, 81803775)
  • the Zhejiang Provincial Natural Science Foundation of China (LQ18H280005, LY21H030002)
  • the Medical Health Science and Technology Project of Zhejiang Provincial Health Commission (2019RC228, 2019RC229, 2019RC113)
  • the Open Foundation from Chinese and Western Integrative Medicine in the Most Important Subjects of Zhejiang , China (ZXYJH2018002)