Nox2 signaling and muscle fiber remodeling are attenuated by losartan administration during skeletal muscle unloading
Open Access
- 5 January 2021
- journal article
- research article
- Published by Wiley in Physiological Reports
- Vol. 9 (1), e14606
- https://doi.org/10.14814/phy2.14606
Abstract
Angiotensin receptor blockade (ARB) reduced unloading‐induced atrophy of skeletal muscle. Losartan mitigated assembly of the Nox2 complex, and thus oxidative stress ARB attenuated loss of sarcolemmal...Keywords
Funding Information
- Sydney and J.L. Huffines Institute for Sports Medicine and Human Performance
- Texas A and M University
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