Self-Motion Signals in Vestibular Nuclei Neurons Projecting to the Thalamus in the Alert Squirrel Monkey
Open Access
- 1 April 2009
- journal article
- research article
- Published by American Physiological Society in Journal of Neurophysiology
- Vol. 101 (4), 1730-1741
- https://doi.org/10.1152/jn.90904.2008
Abstract
Sixty vestibular nuclei neurons antidromically activated by electrical stimulation of the ventroposterior thalamus were recorded in two alert squirrel monkeys. The majority of these neurons were monosynaptically activated by vestibular nerve electrical stimulation. Forty-seven neurons responded to animal rotations around the earth-vertical axis; 16 of them also responded to translations in the horizontal plane. The mean sensitivity to 0.5-Hz rotations of 80°/s velocity was 0.40 ± 0.31 spikes·s−1·deg−1·s−1. Rotational responses were in phase with stimulus velocity. Sensitivities to 0.5-Hz translations of 0.1 g acceleration varied from 92.2 to 359 spikes·s−1· g−1 and response phases varied from 10.1° lead to −98° lag. The firing behavior in 28 neurons was studied during rotation of the whole animal, of the trunk, and voluntary and involuntary rotations of the head. Two classes of vestibulothalamic neurons were distinguished. One class of neurons generated signals related to movement of the head that were similar either when the head and trunk move together or when the head moves on the stationary trunk. A fraction of these neurons fired during involuntary head movements only. A second class of neurons generated signals related to movement of the trunk. They responded when the trunk moved alone or simultaneously with the head, but did not respond to head rotations while the trunk was stationary.Keywords
This publication has 54 references indexed in Scilit:
- Activity of Ventroposterior Thalamus Neurons During Rotation and Translation in the Horizontal Plane in the Alert Squirrel MonkeyJournal of Neurophysiology, 2008
- Vestibular Signals in Primate Thalamus: Properties and OriginsJournal of Neuroscience, 2007
- Activity of Vestibular Nuclei Neurons During Vestibular and Optokinetic Stimulation in the Alert MouseJournal of Neurophysiology, 2007
- Spatial Reference Frames of Visual, Vestibular, and Multimodal Heading Signals in the Dorsal Subdivision of the Medial Superior Temporal AreaJournal of Neuroscience, 2007
- Spatial Properties of Central Vestibular NeuronsJournal of Neurophysiology, 2006
- Multiple Reference Frames for Motion in the Primate CerebellumJournal of Neuroscience, 2004
- Projections of the vestibular nuclei to the thalamus in the rat: APhaseolus vulgaris leucoagglutinin studyJournal of Comparative Neurology, 1999
- Thalamic connections of the vestibular cortical fields in the squirrel monkey (Saimiri sciureus)Journal of Comparative Neurology, 1992
- Thalamic projections of the vestibular nuclei in the cat as revealed by retrograde transport of horseradish peroxidaseNeuroscience Letters, 1978
- Das ReafferenzprinzipThe Science of Nature, 1950