A new homeo-box is present in overlapping cosmid clones which define the mouse Hox-1 locus.
Open Access
- 31 July 1986
- journal article
- research article
- Published by Springer Science and Business Media LLC in The EMBO Journal
- Vol. 5 (8), 1973-1980
- https://doi.org/10.1002/j.1460-2075.1986.tb04452.x
Abstract
A new murine homeo‐box (Hox1‐3) has been isolated and studied with respect to its structure and transcriptional pattern. This homeo‐box is part of a gene which is specifically regulated during mouse prenatal development and expressed in a restricted number of teratocarcinoma tumours as well as in adult testis. Hox1‐3 is shown to be a member of a cluster of at least four homeo‐boxes lying within a 75‐kb segment of DNA on mouse chromosome 6. The structure of the whole cluster, the Hox‐1 locus is presented.This publication has 36 references indexed in Scilit:
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