Induction of an IL7-R+c-Kithi myelolymphoid progenitor critically dependent on IFN-γ signaling during acute malaria
- 2 May 2010
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature Immunology
- Vol. 11 (6), 477-485
- https://doi.org/10.1038/ni.1869
Abstract
Infection elicits cytokine production that can alter hematopoiesis. Potocnik and colleagues identify a unique IL-7R[alpha]+c-Kithi progenitor subset that arises during acute malaria infection and gives rise to predominantly myeloid cells.Keywords
This publication has 50 references indexed in Scilit:
- Migrating monocytes recruited to the spleen play an important role in control of blood stage malariaBlood, 2009
- Selective Expansion of the Monocytic Lineage Directed by Bacterial InfectionThe Journal of Immunology, 2009
- IL-1R Type I-Dependent Hemopoietic Stem Cell Proliferation Is Necessary for Inflammatory Granulopoiesis and Reactive NeutrophiliaThe Journal of Immunology, 2009
- Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infectionBlood, 2008
- Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sitesJCI Insight, 2007
- Concise Review: Stem Cell Antigen-1: Expression, Function, and EnigmaThe International Journal of Cell Cloning, 2007
- Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9Proceedings of the National Academy of Sciences, 2007
- Toll-like Receptors on Hematopoietic Progenitor Cells Stimulate Innate Immune System ReplenishmentImmunity, 2006
- Identification of Flt3+ Lympho-Myeloid Stem Cells Lacking Erythro-Megakaryocytic PotentialCell, 2005
- Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling PathwayScience, 2003