Metal–Organic Framework (MOF)‐Based Drug/Cargo Delivery and Cancer Therapy
Top Cited Papers
- 29 March 2017
- journal article
- review article
- Published by Wiley in Advanced Materials
- Vol. 29 (23)
- https://doi.org/10.1002/adma.201606134
Abstract
Metal–organic frameworks (MOFs)—an emerging class of hybrid porous materials built from metal ions or clusters bridged by organic linkers—have attracted increasing attention in recent years. The superior properties of MOFs, such as well‐defined pore aperture, tailorable composition and structure, tunable size, versatile functionality, high agent loading, and improved biocompatibility, make them promising candidates as drug delivery hosts. Furthermore, scientists have made remarkable achievements in the field of nanomedical applications of MOFs, owing to their facile synthesis on the nanoscale and alternative functionalization via inclusion and surface chemistry. A brief introduction to the applications of MOFs in controlled drug/cargo delivery and cancer therapy that have been reported in recent years is provided here.Keywords
Funding Information
- National Natural Science Foundation of China (51673084, 51473061)
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