OCCURRENCE OF HUMAN PAPILLOMAVIRUS TYPE-16 AND TYPES-18 DNA IN CERVICAL CARCINOMAS FROM JAPAN - AGE OF PATIENTS AND HISTOLOGICAL TYPE OF CARCINOMAS

  • 1 January 1985
    • journal article
    • research article
    • Vol. 76 (8), 667-671
Abstract
By DNA hybridization, human papillomavirus (HPV) types 16 and 18 DNA sequences have been detected in 19 and 3, respectively, out of 56 cervical carcinomas from Japan. Eighteen out of 19 HPV 16-positive specimens were from squamous cell carcinomas, whereas the 3 HPV 18-positive specimens were from a squamous cell carcinoma (1/50), an adenosquamous carcinoma (1/3) and an adenocarcinoma (1/3). The occurrence of HPV 16 DNA decreased in patients over 60 yr odl (.ltoreq. 60 yr, 15/24 (44%); 60 yr <, 4/22 (18%)) (P < 0.05).