Deconvolution of Microfluorometric Histograms withBSplines
- 1 December 1982
- journal article
- research article
- Published by Informa UK Limited in Journal of the American Statistical Association
- Vol. 77 (380), 748-753
- https://doi.org/10.1080/01621459.1982.10477881
Abstract
We consider the problem of estimating a probability density from observations from that density which are further contaminated by random errors. We propose a method of estimation using spline functions, discuss the numerical implementation of the method, and prove its consistency. The problem is motivated by the analysis of DNA content obtained by microfluorometry, and an example of such an analysis is included.Keywords
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