Carcinocythemia (carcinoma cell leukemia). Report of two cases with english literature review
- 1 March 1984
- Vol. 53 (5), 1100-1102
- https://doi.org/10.1002/1097-0142(19840301)53:5<1100::aid-cncr2820530514>3.0.co;2-k
Abstract
Cancer cells of nonhematologic origin are rarely seen on routinely prepared peripheral blood smears. This report describes two patients with disseminated carcinoma, in near terminal state, one with malignant melanoma and another with transitional cell carcinoma of the ureteropelvic junction who developed carcinocythemia (CCA). A review of the English literature revealed only eight other cases in which CCA was documented. Four patients had a small cell bronchogenic (“oat cell”) carcinoma, two had disseminated breast carcinoma and one each had advanced adenocarcinoma of ileum and abdominal rhabdomyosarcoma. The circulating malignant cells usually accounted for less than 10% of the nucleated blood cells, but in one patient comprised up to 80% of the leukocyte count. The mean time between detection of CCA and death was 5 weeks (median, 2 weeks) reflecting the fact that CCA is generally a terminal event. Cancer 53:1100-1102, 1984.This publication has 6 references indexed in Scilit:
- Oat cell carcinoma mimicking leukemiaPostgraduate Medicine, 1980
- Metastatic Carcinoma With Carcinocythemia Mimicking LeukemiaSouthern Medical Journal, 1979
- CARCINOCYTHEMIA DUE TO METASTATIC OAT-CELL CARCINOMA OF THE LUNG1979
- Carcinocythemia (carcinoma cell leukemia) due to metastatic carcinoma of the breast. Report of a caseCancer, 1977
- Carcinocythemia (carcinoma cell leukemia)American Journal Of Medicine, 1976
- Malignant Cells in a Peripheral Blood SmearNew England Journal of Medicine, 1960