Design, construction and use of a large-sample field-cycled PEDRI imager
- 1 July 1998
- journal article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 43 (7), 1877-1886
- https://doi.org/10.1088/0031-9155/43/7/008
Abstract
The design, construction and use of a large-scale field-cycled proton-electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magnet with an internal diameter of 52 cm. The magnetic field can be switched from zero to 59 mT or vice versa in 40 ms. It is used with a double-resonance coil assembly (NMR/EPR) comprising a solenoidal NMR transmit/receive coil and a coaxial, external birdcage resonator for EPR irradiation. Experiments to image the distribution of an exogenous nitroxide free radical in anaesthetized rabbits are described.Keywords
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