Controlling Stem Cell Fate with Material Design
- 28 December 2009
- journal article
- other
- Published by Wiley in Advanced Materials
- Vol. 22 (2), 175-189
- https://doi.org/10.1002/adma.200901055
Abstract
Advances in our understanding of stem cell interactions with their environment are leading to the development of new materials‐based approaches to control stem cell behavior toward cellular culture and tissue regeneration applications. Materials can provide cues based on chemistry, mechanics, structure, and molecule delivery that control stem cell fate decisions and matrix formation. These approaches are helping to advance clinical translation of a range of stem cell types through better expansion techniques and scaffolding for use in tissue engineering approaches for the regeneration of many tissues. With this in mind, this progress report covers basic concepts and recent advances in the use of materials for manipulating stem cells.Keywords
This publication has 140 references indexed in Scilit:
- Adapting collagen/CNT matrix in directing hESC differentiationBiochemical and Biophysical Research Communications, 2009
- Engineering the embryoid body microenvironment to direct embryonic stem cell differentiationBiotechnology Progress, 2009
- Poly(Lactic-co-Glycolic) Acid as a Carrier for Imaging Contrast AgentsPharmaceutical Research, 2008
- Substrate rigidity regulates Ca2+ oscillation via RhoA pathway in stem cellsJournal of Cellular Physiology, 2008
- Controlling poly(β-amino ester) network properties through macromer branchingActa Biomaterialia, 2008
- Osteogenic differentiation of dura mater stem cells cultured in vitro on three-dimensional porous scaffolds of poly(ε-caprolactone) fabricated via co-extrusion and gas foamingActa Biomaterialia, 2008
- The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibersBiomaterials, 2008
- Influence of macromer molecular weight and chemistry on poly(β‐amino ester) network properties and initial cell interactionsJournal of Biomedical Materials Research Part A, 2007
- A fibrinogen-based precision microporous scaffold for tissue engineeringBiomaterials, 2007
- The effect of nanofiber alignment on the maturation of engineered meniscus constructsBiomaterials, 2007