Antibacterial and Antifungal Activity of Zinc(II) Carboxylates With/Without N-Donor Organic Ligands
Open Access
- 1 January 2002
- journal article
- research article
- Published by Hindawi Limited in Metal-Based Drugs
- Vol. 8 (5), 269-274
- https://doi.org/10.1155/mbd.2002.269
Abstract
The antibacterial and antifungal activity of zinc(II) carboxylates with composition (R =H-, , , , , X=Cl, Br, I, n=0 or 2), (Nia=nicotinamide, X=Cl, Br, I) and (Car=caffeine, X=Cl, Br) is studied against bacterial strains Staphylococcus aureus, Escherichia coli and yeast Candida albicans. The structural types are assigned to the prepared compounds and the influence of (i) carboxylate chain length, (ii) substitution of hydrogen atom of carboxylate by halogen and (iii) presence of N-donor organic ligands on the biological activity is discussed.