Circadian Clock in Culture: N -Acetyltransferase Activity of Chick Pineal Glands Oscillates in Vitro
- 16 February 1979
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 203 (4381), 656-658
- https://doi.org/10.1126/science.569904
Abstract
N-Acetyltransferase activity was measured in organ-cultured chick pineal glands. A circadian rhythm of enzyme activity persisted in cultured glands for up to 4 days. The phase of the rhythm in vitro closely approximates its phase in vivo. These observations demonstrate that the pineal gland of chicks contains (or is) a self-sustained circadian oscillator.This publication has 24 references indexed in Scilit:
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