DlCO measurements with gas chromatography
- 1 November 1962
- journal article
- research article
- Published by American Physiological Society in Journal of Applied Physiology
- Vol. 17 (6), 856-860
- https://doi.org/10.1152/jappl.1962.17.6.856
Abstract
A gas chromatograph has been used to analyze gases for the measurement of pulmonary diffusing capacity using the breath-holding technique. The gas mixture used for the measurement consisted of carbon monoxide in air with neon as the insoluble inert gas. The calculated DlCO was unaffected when sulphur hexafloride (SF6) or He was substituted for Ne in the mixture, but since CO and Ne could be most simply and rapidly analyzed, this combination was preferred for the gas mixture used to measure DlCO. The mean DlCO for ten normal subjects was 25.8 ± 4.2 ml/min mm Hg. These results were comparable to values reported in the literature when established methods of analysis were used. An excellent correlation was found between calculated DlCO and the clinical condition of patients with impaired pulmonary diffusing capacity. Submitted on February 14, 1962Keywords
This publication has 6 references indexed in Scilit:
- Application of gas chromatography to respiratory gas analysisJournal of Applied Physiology, 1960
- Solubility of inert gases in human lung tissueJournal of Applied Physiology, 1959
- The Pulmonary Diffusing Capacity in Congenital and Rheumatic Heart DiseaseCirculation, 1959
- The Measurement of Pulmonary Capillary Blood Volume and Pulmonary Membrane Diffusing Capacity in Normal Subjects; The Effects of Exercise and Position12JCI Insight, 1958
- The pulmonary diffusing capacity; a comparison of methods of measurement and a study of the effect of body positionThe Journal of Physiology, 1956
- THE ABSORPTION OF CARBON MONOXIDE BY THE LUNGS DURING BREATHHOLDING 1JCI Insight, 1954