Synthesis, antibacterial and potential anti-HIV activity of some novel imidazole analogs
Open Access
- 1 June 2011
- journal article
- research article
- Published by Walter de Gruyter GmbH in Acta Pharmaceutica
- Vol. 61 (2), 187-201
- https://doi.org/10.2478/v10007-011-0018-2
Abstract
Synthesis, antibacterial and potential anti-HIV activity of some novel imidazole analogs: A series of 1-(2-methyl-4-nitro-imidazol-1-yl)-3-arylaminopropan-2-ones (2a-e), 2-methyl-5-nitro-1-{2-[arylmethoxy] ethyl}-1H-imidazoles (5a-d), and N-(3-hydroxyphenyl)-2-(substituted imidazol-1-yl)alkanamides (8a-e) were synthesized with the aim to develop novel imidazole analogs with broad-spectrum chemotherapeutic properties. Title compounds were evaluated for their anti-HIV and antibacterial activities.Keywords
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