Impact of GHBP interference on estimates of GH and GH pharmacokinetics
- 9 December 2002
- journal article
- research article
- Published by Wiley in Clinical Endocrinology
- Vol. 57 (6), 779-786
- https://doi.org/10.1046/j.1365-2265.2002.01668.x
Abstract
Objective Circulating GH‐binding protein (GHBP) may interfere with GH measurements in immunoassays by competing with the antibodies for ligands. The concentrations of circulating GHBP in humans are c...Keywords
This publication has 29 references indexed in Scilit:
- A simple, rapid immunometric assay for determination of functional and growth hormone‐occupied growth hormone‐binding protein in human serumEuropean Journal of Clinical Investigation, 1996
- Metabolic clearance of recombinant human growth hormone in health and chronic renal failure.JCI Insight, 1994
- Age and Relative Adiposity Are Specific Negative Determinants of the Frequency and Amplitude of Growth Hormone (GH) Secretory Bursts and the Half-Life of Endogenous GH in Healthy Men*Journal of Clinical Endocrinology & Metabolism, 1991
- Effects of Growth Hormone-Binding Proteins on Serum Growth Hormone Measurements*Journal of Clinical Endocrinology & Metabolism, 1991
- In-vivo uptake of human growth hormone in male rat liverJournal of Endocrinology, 1989
- Metabolic Clearance Rates of Synthetic Human Growth Hormone in Lean and Obese Male Rhesus Monkeys*Journal of Clinical Endocrinology & Metabolism, 1988
- Receptor-mediated endocytosis and degradation of bovine growth hormone in rat liverMolecular and Cellular Endocrinology, 1988
- The Effect of Circulating Growth Hormone-Binding Protein on Metabolic Clearance, Distribution, and Degradation of Human Growth Hormone*Journal of Clinical Endocrinology & Metabolism, 1987
- Identification and characterization of specific binding proteins for growth hormone in normal human sera.JCI Insight, 1986
- A Specific Growth Hormone-Binding Protein in Human Plasma: Initial Characterization*Journal of Clinical Endocrinology & Metabolism, 1986