Refining the telomere-telomerase hypothesis of aging and cancer
- 1 July 1996
- journal article
- review article
- Published by Springer Science and Business Media LLC in Nature Biotechnology
- Vol. 14 (7), 836-839
- https://doi.org/10.1038/nbt0796-836
Abstract
While there has been substantial experimental evidence in support of the telomere-telomerase hypothesis of aging and cancer, it has been suggested that the theory has been oversimplified to the exclusion of alternative mechanisms in the progression of cancer. This review strives to present an overview of some of the areas that have not been well explained and to indicate where multiple interpretations of the data are possible.Keywords
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