The Precipitin Test for Bence-Jones Protein

Abstract

IN a previous communication¹ the need for a specific, sensitive test for Bence-Jones protein was stressed. The surprising infrequency with which positive findings for Bence-Jones protein are recorded lends weight to this concept. Of equal importance is the fact that the diagnosis of multiple myeloma, made frequently but late in the course of the disease, might be effected considerably earlier through employment of a more sensitive test for Bence-Jones protein, which, if present, is often the initial indicator of the fundamental pathologic process. A review of the hospital charts of 246 patients with diagnoses of multiple myeloma discloses a high . . .