A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation
- 31 July 2009
- journal article
- research article
- Published by Elsevier BV in Neurobiology of Disease
- Vol. 35 (1), 91-102
- https://doi.org/10.1016/j.nbd.2009.04.007
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- Reduced Sodium Current in Purkinje Neurons from NaV1.1 Mutant Mice: Implications for Ataxia in Severe Myoclonic Epilepsy in InfancyJournal of Neuroscience, 2007
- Characterization of 5′ untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequencesGenomics, 2007
- Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancyNature Neuroscience, 2006
- Persistent Sodium Current in Layer 5 Neocortical Neurons Is Primarily Generated in the Proximal AxonJournal of Neuroscience, 2006
- Single-channel Properties of Human NaV1.1 and Mechanism of Channel Dysfunction in SCN1A-associated EpilepsyThe Journal of general physiology, 2005
- Is phenotype difference in severe myoclonic epilepsy in infancy related to SCN1A mutations?Brain & Development, 2003
- De Novo Mutations in the Sodium-Channel Gene SCN1A Cause Severe Myoclonic Epilepsy of InfancyAmerican Journal of Human Genetics, 2001
- Neuronal Sodium-Channel α1-Subunit Mutations in Generalized Epilepsy with Febrile Seizures PlusAmerican Journal of Human Genetics, 2001
- A sodium channel mutation causing epilepsy in man exhibits subtle defects in fast inactivation and activation in vitroThe Journal of Physiology, 2000
- Functional Co-expression of the β1 and Type IIA α Subunits of Sodium Channels in a Mammalian Cell LinePublished by Elsevier BV ,1995