Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110δ, for relapsed/refractory chronic lymphocytic leukemia
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Open Access
- 29 May 2014
- journal article
- Published by American Society of Hematology in Blood
- Vol. 123 (22), 3390-3397
- https://doi.org/10.1182/blood-2013-11-535047
Abstract
Key Points Idelalisib was evaluated in 54 patients with heavily pretreated chronic lymphocytic leukemia, and target inhibition was documented in vivo. Oral idelalisib therapy demonstrated a favorable safety profile and rapidly induced durable disease control in the majority of patients.Keywords
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