Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1

Abstract
Botulinum neurotoxins (BoNTs), the causative agent of human botulism, are the most potent naturally occurring toxins known. BoNT/A1, the most studied BoNT, is also used as an important biopharmaceuti...
Funding Information
  • University of Wisconsin, Madison
  • National Institute of Allergy and Infectious Diseases (R21AI082826)
  • NIH/NIAID Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research (RCE) Program
  • Pacific Southwest Regional Center of Excellence grant (U54 AI065359)
  • Great Lakes Regional Center of Excellence (U54 AI057153)