Compounds produced from potential tunicate-blue-green algal symbiosis: A review
- 1 November 1996
- journal article
- review article
- Published by Oxford University Press (OUP) in Journal of Industrial Microbiology & Biotechnology
- Vol. 17 (5-6), 385-396
- https://doi.org/10.1007/bf01574769
Abstract
Tunicates of the family Didemnidae can be host to two genera of blue-green algae:Synechocystis andProchloron. The presence of symbiotic algae raises questions as to the exact origin of the biologically important metabolites which have been isolated from tunicates in recent years. Is the compound produced by the tunicate, the alga, or through a combined effort of both organisms? Although this question cannot be fully addressed at the present time, there is evidence which supports the argument that the metabolic origin of certain ascidian metabolites resides in the alga, or is due to a collaborative effort of both organisms. The purpose of this review is to present compounds isolated from tunicates that possess a likely symbiotic relationship with eitherSynechocystis orProchloron. Attention will also be given to the ecology of the organisms and the biological activities of metabolites isolated.Keywords
This publication has 63 references indexed in Scilit:
- Tyr5didemnin B and [D-Pro4]didemnin B; Two new natural didemnins with a modified macrocycleTetrahedron, 1995
- Immunology: a look toward the sea and what we have learned from tunicatesAquaculture, 1995
- Bistramides A, B, C, D, and K: A New Class of Bioactive Cyclic Polyethers from Lissoclinum bistratumJournal of Natural Products, 1994
- The complete spectral assignment of didemnin H a new constituent of the tunicate Trididemnum cyanophorumTetrahedron Letters, 1994
- Studies of Australian Ascidians. IV. Mollamide, a Cytotoxic Cyclic Heptapeptide From the Compound Ascidian Didemnum molleAustralian Journal of Chemistry, 1994
- Metabolic integration between symbiotic cyanobacteria and sponges: a possible mechanismMarine Biology, 1993
- Ascidians: producers of amino acid-derived metabolitesChemical Reviews, 1993
- Novel cytotoxic compounds from the ascidian Lissoclinum bistratumJournal of Medicinal Chemistry, 1989
- Patellazole B: a novel cytotoxic thiazole-containing macrolide from the marine tunicate Lissoclinum patellaJournal of the American Chemical Society, 1988
- Tunichlorin: a nickel chlorin isolated from the Caribbean tunicate Trididemnum solidum.Proceedings of the National Academy of Sciences of the United States of America, 1988