1. An account of fifty-four patients suffering from ainhum is presented, and the clinical and pathological findings are discussed. 2. Etiology is considered, and a plan of treatment proposed. 3. Ainhum in Ibadan is a disease of all ages and both sexes. 4. Most patients have considerable pain. 5. It is due to a non-inflammatory change in the basal layer of the epidermis. 6. Surgical treatment has gratifying results.