Activation of Serum Lactic Dehydrogenase

Abstract

THREE lactic acid dehydrogenase (LDH) isozyme patterns are known to be associated with increased serum LDH activities¹ (Fig. 1). One common pattern, called the alpha LDH abnormality, is associated with erythrocyte hemolysis and with injuries of the renal cortex and myocardium. A second common pattern, called the beta-gamma LDH abnormality, is associated with injuries of the liver, skeletal muscle and skin. A much less common pattern, called the isomorphic LDH abnormality, is associated with some types of proliferative and disseminated neoplastic diseases. The alpha and beta-gamma LDH abnormalities precisely reflect the LDH isozyme patterns found in the . . .