Bestimmung der Glucose-6-Phosphatdehydrogenase- Aktivität in den Erythrozyten zur Erkennung von hypo- und aplastischer Erythropoese

Abstract

Fhe decrease in glucose-6-phosphate dehydrogenase activity during the process of physiological aging of erythrocytes is used to assess the average age of an erythrocyte population. By taking the hemoglobin content of the whole blood into consideration, the rate of effective erythropoiesis can be estimated. A suitable reference system is outlined for comparing the effective erythropoiesis in various types of anemia. The results in various blood dyscrasias and the modification of effective erythropoiesis by treatment are reported and discussed.