Saponins from the Bark of Nephelium maingayi
- 18 December 2003
- journal article
- review article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 67 (2), 201-205
- https://doi.org/10.1021/np030389e
Abstract
Activity-guided fractionation of the bark of Nephelium maingayi, collected in Indonesia, led to the isolation of six new saponins (1−6). The aglycon of 4 was determined to be a new compound, 7α-methoxyerythrodiol, and those of 1−3 and of 5 and 6 were identified as erythrodiol and maniladiol (16β-hydroxyamyrin), respectively. The structures of 1−6 were determined on the basis of spectral data interpretation, and the absolute configurations of their component monosaccharides were determined as their thiazolidine derivatives after acid hydrolysis. Of the isolates, only compounds 1 and 5 showed very weak cytotoxic activity against a panel of human tumor cell lines.Keywords
This publication has 7 references indexed in Scilit:
- Novel strategies for the discovery of plant-derived anticancer agentsPublished by Walter de Gruyter GmbH ,1999
- Comparative content of total polyphenols and dietary fiber in tropical fruits and persimmonThe Journal of Nutritional Biochemistry, 1999
- Inhibitory effects of Indonesian medicinal plants on the infection of herpes simplex virus type 1Phytotherapy Research, 1999
- The Occurrence and Characteristics of Long Chain Polyprenols from Leaves of SapindaceaeJournal of Plant Physiology, 1995
- Gas-liquid chromatographic separation of aldose enantiomers as trimethylsilyl ethers of methyl 2-(polyhydroxyalkyl)-thiazolidine-4(R)-carboxylates.CHEMICAL & PHARMACEUTICAL BULLETIN, 1987
- Structure of (+)-rangiformic acidPhytochemistry, 1983
- Fatty acid compostion of the oil of the rambutan,Nephelium lappaceum, and of the flame of the forest,Delonix regiaJournal of the Science of Food and Agriculture, 1969