Global epidemiology of urinary tract infections
Top Cited Papers
- 1 February 2016
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Current Opinion in Infectious Diseases
- Vol. 29 (1), 73-79
- https://doi.org/10.1097/qco.0000000000000228
Abstract
Both in the community and hospital setting, urinary tract infections (UTIs) are common. Initial appropriate empirical treatment requires a good knowledge of epidemiological data. In this review, the most recent global epidemiological data of UTIs have been summarized. Community-associated UTI (CAUTI) prevalence is 0.7% and the main risk factors are age, history of UTI, sexual activity and diabetes. The most common pathogen is Escherichia coli and resistance rates to common antibiotics depend very much on the geographical location. The lowest observed resistance was for fosfomycin (range: 0-2.9%), nitrofurantoin (range: 0-4.4%) and mecillinam (range: 0-4%). Healthcare-associated UTI (HAUTI) frequency among HCAIs is 12.9 (confidence interval: 10.2-16%), 19.6 and 24% in the United States, Europe and developing countries, respectively. In urology departments, the prevalence is 5.1%. Resistance to almost all antibiotics in HAUTIs is above 20% and there is a significant geographical variation. Community onset HAUTIs bacterial spectrum is similar to hospital onset HAUTIs and different from CAUTIs. It is challenging to provide with an exact frequency of UTIs. Both CAUTI and HAUTI frequency, pathogen spectrum and resistance rates vary according to geographical setting.Keywords
This publication has 30 references indexed in Scilit:
- Symptoms and Risk Factors Associated with First Urinary Tract Infection in College Age Women: A Prospective Cohort StudyJournal of Urology, 2013
- Community-onset healthcare-related urinary tract infections: Comparison with community and hospital-acquired urinary tract infectionsJournal of Infection, 2012
- Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistanceClinical Microbiology & Infection, 2012
- Trends in Catheter-Associated Urinary Tract Infections in Adult Intensive Care Units—United States, 1990–2007Infection Control & Hospital Epidemiology, 2011
- Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysisThe Lancet, 2011
- Guideline for Prevention of Catheter-Associated Urinary Tract Infections 2009Infection Control & Hospital Epidemiology, 2010
- Prevalence and factors associated with urinary tract infections (UTIs) in very old womenArchives of Gerontology and Geriatrics, 2009
- Sexual Intercourse and Risk of Symptomatic Urinary Tract Infection in Post-Menopausal WomenJournal of General Internal Medicine, 2008
- Adherence to the Infectious Diseases Society of America Guidelines in the Treatment of Uncomplicated Urinary Tract InfectionClinical Infectious Diseases, 2007
- UROLOGIC DISEASES IN AMERICA PROJECT: TRENDS IN RESOURCE USE FOR URINARY TRACT INFECTIONS IN WOMENJournal of Urology, 2005