Inhibition of Ligand-independent ERK1/2 Activity in Kidney Proximal Tubular Cells Deprived of Soluble Survival Factors Up-regulates Akt and Prevents Apoptosis
Open Access
- 1 March 2004
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 279 (12), 10962-10972
- https://doi.org/10.1074/jbc.m312048200
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- ATP Depletion Of Tubular Cells Causes Dissociation of the Zonula Adherens and Nuclear Translocation of β-Catenin and LEF-1Journal of the American Society of Nephrology, 2002
- Inhibition of Akt and Its Anti-apoptotic Activities by Tumor Necrosis Factor-induced Protein Kinase C-related Kinase 2 (PRK2) CleavageJournal of Biological Chemistry, 2000
- Specificity and mechanism of action of some commonly used protein kinase inhibitorsBiochemical Journal, 2000
- 90-kDa Ribosomal S6 Kinase Is Phosphorylated and Activated by 3-Phosphoinositide-dependent Protein Kinase-1Journal of Biological Chemistry, 1999
- Intracellular signalling: PDK1 – a kinase at the hub of thingsCurrent Biology, 1999
- Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTENCell, 1998
- Molecules in focus: The c-Cbl oncoproteinThe International Journal of Biochemistry & Cell Biology, 1998
- PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in VivoJournal of Biological Chemistry, 1995
- Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinaseTrends in Biochemical Sciences, 1995
- Induction of apoptosis in fibroblasts by c-myc proteinCell, 1992