HMG‐CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis
Open Access
- 10 March 2004
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 89 (1), 24-32
- https://doi.org/10.1046/j.1471-4159.2003.02305.x
Abstract
To determine whether neurite outgrowth depends upon the mevalonate pathway, we blocked mevalonate synthesis in nerve growth factor-treated PC12 cells or primary cortical neurones with atorvastatin, a...Keywords
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