Extreme Toxicity from Combustion Products of a Fire-Retarded Polyurethane Foam
- 28 February 1975
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 187 (4178), 742-744
- https://doi.org/10.1126/science.1114319
Abstract
The products from nonflaming combustion of wood and a trimethylol-propane-based rigid-urethane foam that was not fire-retarded produced elevated carboxyhemoglobin levels but no abnormal neurological effects. However, when this type of foam contained a reactive phosphate fire retardant, the combustion products caused grand mal seizures and death in rats. The toxic combustion product responsible for the seizures has been identified as 4-ethyl-1-phospha-2,6,7-trioxabicyclo(2.2.2.)octane-1-oxide.Keywords
This publication has 3 references indexed in Scilit:
- The identification of a highly toxic bicyclophosphate in the combustion products of a fire‐retarded urethane foamJournal of Polymer Science Part C: Polymer Letters, 1975
- Smoke development at different energy flux levels in an NBS smoke density chamberFire Technology, 1974
- Bicyclic Phosphorus Esters: High Toxicity without Cholinesterase InhibitionScience, 1973