Use of Sephadex column chromatography in the assessment of thyroid status
Open Access
- 1 March 1967
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 20 (2), 170-174
- https://doi.org/10.1136/jcp.20.2.170
Abstract
A method is described for assessing thyroid status using Sephadex column chromatography of serum samples with added 125I triiodothyronine. The method is simple and inexpensive. It gave a correct diagnostic result in 97% of 258 euthyroid, 90% of 80 hyperthyroid, 78% of 59 hypothyroid, and 67% of 50 euthyroid, ill patients. The principle of the method and its limitations are briefly discussed.This publication has 6 references indexed in Scilit:
- THE BINDING OF 131I-TRIIODOTHYRONINE BY SERUM PROTEINS AS AN IN VITRO TEST OF THYROID FUNCTIONActa Endocrinologica, 1964
- THEIN VITRORESIN SPONGE UPTAKE OF TRTIODOTHYRONINE-I131FROM SERUM IN THYROID DISEASE AND IN PREGNANCY*Journal of Clinical Endocrinology & Metabolism, 1960
- LABELING OF ERYTHROCYTESIN VITROWITH RADIOIODINE-TAGGEDl-TRIIODOTHYRONINE AS AN INDEX OF THYROID FUNCTION: AN IMPROVED HEMATOCRIT CORRECTION*Journal of Clinical Endocrinology & Metabolism, 1960
- Proteins Associated with the Thyroid HormonesPhysiological Reviews, 1960
- Serum proteins, including thyroxine-binding proteins, in maternal and foetal rabbitsThe Journal of Physiology, 1959
- THE THYROID HORMONE-PLASMA PROTEIN COMPLEX IN MAN. II. A NEWIN VITROMETHOD FOR STUDY OF “UPTAKE” OF LABELLED HORMONAL COMPONENTS BY HUMAN ERYTHROCYTES*†Journal of Clinical Endocrinology & Metabolism, 1957