Molecular Machines
- 15 August 2004
- journal article
- review article
- Published by Annual Reviews in Annual Review of Biomedical Engineering
- Vol. 6 (1), 363-395
- https://doi.org/10.1146/annurev.bioeng.6.040803.140143
Abstract
▪ Abstract Molecular machines are tiny energy conversion devices on the molecular-size scale. Whether naturally occurring or synthetic, these machines are generally more efficient than their macroscale counterparts. They have their own mechanochemistry, dynamics, workspace, and usability and are composed of nature's building blocks: namely proteins, DNA, and other compounds, built atom by atom. With modern scientific capabilities it has become possible to create synthetic molecular devices and interface them with each other. Countless such machines exist in nature, and it is possible to build artificial ones by mimicking nature. Here we review some of the known molecular machines, their structures, features, and characteristics. We also look at certain devices in their early development stages, as well as their future applications and challenges.Keywords
This publication has 100 references indexed in Scilit:
- Functional Rotaxanes: From Controlled Molecular Motions to Electron Transfer Between Chemically Nonconnected ChromophoresChemistry – A European Journal, 1998
- Kinesin: What Gives?Cell, 1998
- A Light‐Induced Molecular Shuttle Based on a [2]Rotaxane‐Derived TriadAngewandte Chemie-International Edition, 1993
- Symmetric immobile DNA branched junctionsBiochemistry, 1993
- A spring-loaded mechanism for the conformational change of influenza hemagglutininCell, 1993
- M ring, S ring and proximal rod of the flagellar basal body of Salmonella typhimurium are composed of subunits of a single protein, FliFJournal of Molecular Biology, 1992
- Additional structures associated with bacterial flagellar basal bodyJournal of Molecular Biology, 1990
- Correlated rotation in complex triarylmethanes. I. 32-Isomer system and residual diastereoisomerismJournal of the American Chemical Society, 1974
- Correlated rotation in complex triarylmethanes. II. 16- and 8-Isomer systems and residual diastereotopicityJournal of the American Chemical Society, 1974
- Substructure of the myosin moleculeJournal of Molecular Biology, 1971