A Randomized Trial of Prednisolone in Patients with Severe Alcoholic Hepatitis
- 20 February 1992
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 326 (8), 507-512
- https://doi.org/10.1056/nejm199202203260802
Abstract
Controlled trials have yielded inconsistent results with regard to the efficacy of corticosteroids in the treatment of alcoholic hepatitis. Three meta-analyses suggest that they may be effective in patients with encephalopathy who have severe liver disease.Keywords
This publication has 9 references indexed in Scilit:
- Do Corticosteroids Reduce Mortality from Alcoholic Hepatitis?Annals of Internal Medicine, 1990
- Alcoholic Hepatitis: Pathogenesis and Approaches to TreatmentScandinavian Journal of Gastroenterology, 1990
- Intestinal endotoxins as mediators of hepatic injury—An idea whose time has come againHepatology, 1989
- Methylprednisolone Therapy in Patients with Severe Alcoholic HepatitisAnnals of Internal Medicine, 1989
- Is therapy with testosterone or anabolic-androgenic steroids useful in the treatment of alcoholic liver disease?Hepatology, 1986
- Effects of dexamethasone on albumin and collagen gene expression in primary cultures of adult rat hepatocytesHepatology, 1985
- Steroid treatment of alcoholic hepatitisGastroenterology, 1978
- Alcoholic HepatitisAnnals of Internal Medicine, 1971
- Prognosis in Acute Liver Disease of the Alcoholic PatientNew England Journal of Medicine, 1966