Preliminary Evaluation of an Immunochromatographic Strip Test for SpecificTreponema pallidumAntibodies
Open Access
- 1 August 2002
- journal article
- research article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 40 (8), 3064-3065
- https://doi.org/10.1128/jcm.40.8.3064-3065.2002
Abstract
We evaluated a prototype immunochromatographic strip (ICS) test for qualitative detection ofTreponema pallidumantibodies in 353 sera from 157 patients. For sera from 43 syphilis patients, the ICSs were reactive, while for sera from 114 patients without syphilis, including 22 with biologically false-positive Rapid Plasma Reagin test results, the ICSs were nonreactive. The ICS test may expand the available options for serological testing for syphilis.Keywords
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- Humoral immune response in human syphilis to polypeptides of Treponema pallidum.The Journal of Immunology, 1982