Comparison of Pituitary-Adrenocortical Response to Hypoglycaemia and Surgery
- 1 February 1979
- journal article
- research article
- Published by Wiley in Acta Anaesthesiologica Scandinavica
- Vol. 23 (1), 103-106
- https://doi.org/10.1111/j.1399-6576.1979.tb01428.x
Abstract
The hypothalamic-pituitary-adrenocortical (HPA) responses to the hypoglycaemic stimulus and to operation (laparotomy) are compared. The studies were carried out in eight patients who were subjected to insulin-induced hypoglycaemia on the day before elective abdominal surgery. Plasma corticotrophin (ACTH) and plasma cortisol concentration increases were virtually indentical during the two procedures, which suggests that hypoglycaemia and surgical trauma are comparable stress factors and that the hypoglycaemia test is reliable in predicting the HPA responses to major surgical trauma.Keywords
This publication has 3 references indexed in Scilit:
- PITUITARY-ADRENAL RESPONSE TO SURGICAL STRESS IN PATIENTS RECEIVING CORTICOTROPHIN TREATMENTThe Lancet, 1970
- The adrenocortical response to surgery and insulin-induced hypoglycaemia in corticosteroid-treated and normal subjectsBritish Journal of Surgery, 1969
- Studies on the Specificity of Fluorimetric Determination of Plasma Corticosteroids ad Modum De Moor & SteenoScandinavian Journal of Clinical and Laboratory Investigation, 1967