Evaluating the Degree of Conformity of Papillary Carcinoma and Follicular Carcinoma to the Reported Ultrasonographic Findings of Malignant Thyroid Tumor
Open Access
- 1 January 2007
- journal article
- Published by The Korean Society of Radiology in Korean Journal of Radiology
- Vol. 8 (3), 192-197
- https://doi.org/10.3348/kjr.2007.8.3.192
Abstract
We wanted to evaluate the degree of conformity of papillary carcinoma and follicular carcinoma to the reported ultrasonographic findings of malignant thyroid tumor. Between January 2003 and December 2004, fine needle aspiration biopsy was performed in 1,036 patients with palpable and nonpalpable thyroid lesions. We retrospectively reviewed the ultrasonographic findings of patients with papillary carcinomas (n = 127) and follicular carcinomas (n = 23) that were proven by operation or fine needle aspiration biopsy. We analyzed the ultrasonographic findings of these nodules based on the reported ultrasonographic findings of malignant thyroid tumor: hypoechogenicity, a taller than wide orientation, a microlobulated or irregular margin, a thick hypoechoic rim (halo sign), microcalcification and cystic change. The echogenicity was hypoechoic in 72.4% (92/127) of the papillary carcinomas, but it was isoechoic in 65.2% (15/23) of the follicular carcinomas (p < 0.001). The nodule shape was tall or round in 74.1% of the papillary carcinomas, but it was flat in 72.7% of the follicular carcinomas (p < 0.001). The tumor margin was microlobulated or irregular in 92.9% of the papillary carcinomas and in 60.9% of the follicular carcinomas (p < 0.001). A hypoechoic rim was seen in 26% of the papillary carcinomas (thin rim: 13.4%, thick rim: 12.6%) and in 86.6% of the follicular carcinomas (thin rim: 39.1%, thick rim: 47.8%, p < 0.001). Microcalcifications were demonstrated in 33.9% of the papillary carcinomas and in none of the cases of follicular carcinoma (p < 0.001). A solid mass without cystic change were seen in 98.4% of the papillary carcinomas and in 82.6% of the follicular carcinomas (p < 0.001). The previously reported ultrasonography findings of malignant thyroid tumor are in conformity with most of the papillary carcinomas, but not with follicular carcinomas. The current ultrasonographic features for thyroid malignancy should be cautiously applied as the indication for needle aspiration biopsy so that follicular carcinomas are not missed by too narrow and strict biopsy criteria.Keywords
This publication has 11 references indexed in Scilit:
- Management of Thyroid Nodules Detected at US: Society of Radiologists in Ultrasound Consensus Conference StatementRadiology, 2005
- Distinct Diagnostic Criteria for Ultrasonographic Examination of Papillary Thyroid Carcinoma: A Multicenter StudyThyroid®, 2005
- Diagnosis of Thyroid Follicular Carcinoma by the Vascular Pattern and Velocimetric Parameters Using High Resolution Pulsed and Power Doppler UltrasonographyEndocrine Journal, 2005
- Clinical Evaluation of Color Doppler Imaging for the Differential Diagnosis of Thyroid Follicular LesionsWorld Journal of Surgery, 2004
- Risk for Malignancy of Thyroid Nodules as Assessed by Sonographic CriteriaJournal of Ultrasound in Medicine, 2004
- Ultrasonography‐guided fine‐needle aspiration of thyroid incidentaloma: correlation with pathological findingsClinical Endocrinology, 2003
- Common and Uncommon Sonographic Features of Papillary Thyroid CarcinomaJournal of Ultrasound in Medicine, 2003
- Sonographic Features of Benign Thyroid NodulesJournal of Ultrasound in Medicine, 2003
- Can Color Doppler Sonography Aid in the Prediction of Malignancy of Thyroid Nodules?Journal of Ultrasound in Medicine, 2003
- New Sonographic Criteria for Recommending Fine-Needle Aspiration Biopsy of Nonpalpable Solid Nodules of the ThyroidAmerican Journal of Roentgenology, 2002