Antigen-specific T-cell factor in cell cooperation. Mapping within the I region of the H-2 complex and ability to cooperate across allogeneic barriers.
Open Access
- 1 September 1975
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 142 (3), 694-700
- https://doi.org/10.1084/jem.142.3.694
Abstract
Further mapping of the mouse T-cell factor specific for poly(Try,Glu)-polyD-LAla--polyLys is reported. It is shown to be a product of the I-A subregion of the H-2 complex by the use of antisera either raised specifically against or made specific, by absorption, for different regions of the H-2 complex. The factor cooperates across allogeneic barriers, e.g., when factor produced by one strian is combined with bone marrow cells of other H-2 incompatible strains.Keywords
This publication has 6 references indexed in Scilit:
- Antigen-specific T-cell factors in the genetic control of the immune response to poly(Tyr,Glu)-polyDLAla--polyLys. Evidence for T- and B-cell defects in SJL mice.The Journal of Experimental Medicine, 1975
- Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complexThe Journal of Experimental Medicine, 1975
- The H-2 Major Histocompatibility Complex and the/Immune Response Region: Genetic Variation, Function, and OrganizationAdvances in Immunology, 1975
- ANTIGEN-SPECIFIC T-CELL FACTOR IN CELL COOPERATION: PHYSICAL PROPERTIES AND MAPPING IN THE LEFT-HAND (K) HALF OF H-2The Journal of Experimental Medicine, 1974
- T cell factor which can replace T cells in vivoNature, 1974
- Antigen design and immune response.1973