Single-Walled Carbon Nanotubes in the Intact Organism: Near-IR Imaging and Biocompatibility Studies in Drosophila
- 16 August 2007
- journal article
- letter
- Published by American Chemical Society (ACS) in Nano Letters
- Vol. 7 (9), 2650-2654
- https://doi.org/10.1021/nl0710452
Abstract
The ability of near-infrared fluorescence imaging to detect single-walled carbon nanotubes (SWNTs) in organisms and biological tissues has been explored using Drosophila melanogaster (fruit flies). Drosophila larvae were raised on food containing ∼10 ppm of disaggregated SWNTs. Their viability and growth were not reduced by nanotube ingestion. Near-IR nanotube fluorescence was imaged from intact living larvae, and individual nanotubes in dissected tissue specimens were imaged, structurally identified, and counted to estimate a biodistribution.Keywords
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