Lignins from Agroindustrial by-Products as Natural Ingredients for Cosmetics: Chemical Structure and In Vitro Sunscreen and Cytotoxic Activities
Open Access
- 2 March 2020
- Vol. 25 (5), 1131
- https://doi.org/10.3390/molecules25051131
Abstract
The growing concern about the environmental impact and human health risk related to the excessive use of synthetic ingredients in cosmetics and topical formulations calls for the exploration of safe and sustainable natural alternatives. Lignin-rich lignocellulosic industrial wastes such as hazelnut and walnut shells were used as a lignin polymer source. Agro-derived lignins were evaluated as a potential natural active ingredient for health care products. Aside from the structural characteristics of isolated lignins, which were identified by GPC, Py-GC–MS, and 2D HSQC NMR techniques, functional properties such as antioxidant power and UV absorption ability were investigated. The SPF values found for creams containing 5% of hazelnut and walnut lignin content were 6.9 and 4.5, respectively. Additionally, both lignin types presented appropriate protection against UVA radiation, highly interesting property to block the full ultraviolet spectrum. The biological activity of isolated lignins assessed at different concentrations (0.01–1 mg/mL) and different times (24, 48, and 72 h) on murine fibroblast cell line 3T3 suggested their suitability for cosmetic applications.Keywords
This publication has 58 references indexed in Scilit:
- First Determination of UV Filters in Marine Mammals. Octocrylene Levels in Franciscana DolphinsEnvironmental Science & Technology, 2013
- Detection and Structural Characterization of Thermally Generated Isoflavone Malonylglucoside DerivativesJournal of Agricultural and Food Chemistry, 2010
- Effect of the Temperature on the Composition of Lignin Pyrolysis ProductsEnergy & Fuels, 2010
- Widespread occurrence of estrogenic UV-filters in aquatic ecosystems in SwitzerlandEnvironmental Pollution, 2010
- HSQC-NMR analysis of lignin in woody (Eucalyptus globulus and Picea abies) and non-woody (Agave sisalana) ball-milled plant materials at the gel state 10th EWLP, Stockholm, Sweden, August 25–28, 2008Holzforschung, 2009
- Potential applications of antioxidant lignins from different sourcesIndustrial Crops and Products, 2008
- Effects of the UV filter benzophenone-2 on reproduction in fishToxicology and Applied Pharmacology, 2007
- Organosolv Ethanol Lignin from Hybrid Poplar as a Radical Scavenger: Relationship between Lignin Structure, Extraction Conditions, and Antioxidant ActivityJournal of Agricultural and Food Chemistry, 2006
- Characterization of the radical scavenging activity of lignins??natural antioxidantsBioresource Technology, 2004
- Effect of butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) on rat erythrocytesEnvironmental Research, 1986