METABOLIC ACTIVITIES OF VITAMIN D IN ANIMALS

Abstract

Considerable amounts of the sulfate were formed in the liver, but extremely poor in other tissues. Vitamin D-sulfokinase was isolated from rat-liver homogenate, and the optimum conditions were investigated. Isotopic investigation for the biogenesis of vitamin D sulfate was carried out using the vitamin D-sulfokinase preparation. The activity of the vitamin D2-sulfo-kinase preparation was estimated to be 3.3% as estimated from the yield of vitamin D2 sulfate from the vitamin D2 employed.