Avian polyneuritis

Abstract

The minced cerebrum of the vitamin B1-deficient pigeon readily removes lactate in vitro. Addition of small amounts of vitamin B1 concentrate causes no significant increase in the amount of lactate removed, but increases the O uptake in the presence of added lactate. The lesion in vitamin B1-deficient brain affects an oxidase system that is associated with lactate, but is not concerned with the removal of lactate itself in isolated brain tissue.