Treatment of Bechcet's syndrome with transfer factor

Abstract

Six patients with Behcet''s syndrome were treated with transfer factor (TF) from randomly selected donors. Mucocutaneous symptoms and signs were predominant at the time that TF injections were started. Three patients showed great improvement, 1 showed moderate improvement, and 1 was unresponsive to multiple injections of TF from different donors. One case was uninterpretable because of concomitant administration of high doses of prednisone and chlorambucil and brief treatment with TF. TF therapy may be beneficial in some patients with Behcet''s syndrome. A trial of TF is warranted at least in the absence of severe ocular or neurologic manifestations.