Structure and Function in the Nucleus
- 24 April 1998
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 280 (5363), 547-553
- https://doi.org/10.1126/science.280.5363.547
Abstract
Current evidence suggests that the nucleus has a distinct substructure, albeit one that is dynamic rather than a rigid framework. Viral infection, oncogene expression, and inherited human disorders can each cause profound and specific changes in nuclear organization. This review summarizes recent progress in understanding nuclear organization, highlighting in particular the dynamic aspects of nuclear structure.Keywords
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